Vipadika is one form of the Kushtha with Pani Pada Sputhana (cracking of the skin in the palms and soles) and Teevra Vedana (severe pain) as the cardinal symptoms. It can be correlated with Palmoplantar psoriasis (PPP) having symptoms fissuring of skin in the palms and soles, severe pain, burning, itching and roughness. It is Vata-kaphaj Kushtha. In the pathogenesis of Kushtha, Tridoshas, Twacha, Rakta, Mamsa and Lasika are involved. In this case, treatment was planned to alleviate Vata and Kapha Dosha. Twak, Rakta, Mamsa and Lasika Dushya were treated effectively. Kushthaghna medicines were used along with this. In the end, significant results were found in the patient.