Data Mining is special and important technique utilized to have better business solutions. General survey on Data Mining Techniques, Methods, Tools and Challenges of Data Mining in all the domains, is at most important and so much in demand, applying machine learning concepts and techniques in medical field is also most essential in the present scenario. In this paper the following chapters are presented- various data mining techniques, merits and demerits of data mining, open source data mining tools available, and also domains or industries applied DM.