Introduction: Gestational diabetes mellitus (GDM) is one of the most common medical disorders complicating pregnancy, and it usually resolves following delivery. However, GDM can affect the immediate maternal and perinatal outcomes, besides, it can also have long-lasting health consequences for both the mother and the newborn. Evidence from experimental studies has shown that higher than normal ferritin concentrations can lead to pancreatic __ampersandsignbeta; cell dysfunction and impaired glucose metabolism and GDM. Objective: Estimation of serum ferritin in early pregnancy in normal controls and women suffering from GDM. Methods: 50 Pregnant women (24-28 weeks gestation) were divided into GDM cases (n=35) and normal controls (n=15). Blood samples were collected for estimation of HbA1c and serum ferritin and the results were analysed statistically. Results: The values of initial DIPSI 2 hr blood glucose, and later HbA1c and serum ferritin were significantly higher (p__ampersandsignlt; 0.05) in GDM cases in comparison to the control group. Conclusion: Serum ferritin is significantly higher in patients of GDM, pointing towards a possible role of oxidative stress in GDM as well as fetal intra-uterine and postpartum well being.