Cancer, which is also called malignancy, is an abnormal growth of cells. There are more than 200 types of cancers including skin cancer, lung cancer, breast cancer, colon cancer, prostate cancer, lymphoma etc....Cancer treatments are varying like chemotherapy, radiation therapy , surgery etc... but these can be effective only in a subset of the population. Thus, the inherent variability of cancer has led itself to the growing field of precision medicine. Precision medicine plays a major role in cancer therapy. Precision medicine involves the usage of genetic changes in a patient__ampersandsignrsquo;s tumor to determine the type of treatment one has to undergo. Precision medicine is an approach to patient care that allows doctors to select treatments that help patients based on a genetic understanding of their disease. This review highlighted the importance and role of precision medicine in cancer therapy.