Background: Differences in incidence and pattern of oral cancer can be due to the overall effects of the prevalence of specific risk factors in a sample population. The low-income groups are at a wide exposure to risk factors such as tobacco chewing, gutka consumption, smoking, etc. Objective: The aim of this epidemiological study is to determine the association of deleterious habits already deemed as risk factors in patients with oral cancer at our centre. Methods: A retrospective analysis of patients undergoing treatment for oral cancer in our institution was done to identify patients with a positive association to habits - pan chewing, smoking, and gutka consumption. Statistical analysis was performed using the Chi-square test after data collection using SPSS software version 20. Results: Out of 48, 40 patients were included for the study based on the inclusion criteria. Females had no habits (20%), while males reported an incidence of pan chewing habit (15%), and gutka consumption (10%). Overall patients undergoing treatment for oral cancer with exposure to risk factors were 35% while 65% of patients had no association with deleterious habits and risk factors associated with oral cancer. A significant association was found between the prevalence of no habits and middle age group individuals. Conclusion: The study observed a trend towards a higher incidence of oral cancer in patients without exposure to deleterious habits. This strengthens the association of incidence of oral cancer with the genetic constitution of the individual and / or other risk factors not studied here. Many cancer registries should be scanned for confirmation of this trend shift elsewhere in the nation. Clinical Significance: Genetic and molecular analysis of specimens can help shed light on the etiological factors responsible for oral cancer in patients.