Background: The spread of Corona disease has created different types of speculation in the mind of every human being. The World Health Organisation (WHO) declared it as a Pandemic. To control the multiplicity of this virus, the Govt. of India declaredlockdown from 25th March-2020 and now it is in the unlock stage. During this nationwide lockdown, people all over the country are not able to move from one place to another. As a result, some persons have been living alone for a long time. They are deprived of meeting their near and dear ones. Objectives: This study aims at understanding the relationship between the living conditions of a person during lockdown with the different aspect of mental health; such as level of depression, level of anxiety and level of stress. Methods: Convenient Sampling is used for data collection through structured e-questionnaire. Chi-Square Test is used to study the level of significance among the different category of variables. Results: The analysis shows that p=0.003 between living condition and level of depression, p=0.036 between living condition and Level of anxiety and p=0.004 between living condition and level of stress. Conclusion: The living condition a person affects mental health. It has a great effect on the level of depression, anxiety and stress. The mental well being should be maintained with proper stress management activities. Conclusion: From this study, we can conclude that Kamal Patra can resist the toxic effects of Dhatura up to some extent.