Introduction: Dry eye is the most common ocular disorder manifested by tear deficiency resulting in discomfort in eyes, visual disturbances, and instability in tear film with a surplus of alternative symptoms like burning of eyes, photophobia, tearing, ocular fatigue, and grittiness that hinder activities of daily living (ADL), therefore compromising the patient__ampersandsignrsquo;s quality of life. Flaxseed is considered as an emerging food with nutritional characteristics loaded with essential polyunsaturated Omega-3 fatty acids with anti-inflammatory properties. The evidence shows a beneficial effect of nutraceutical supplements containing omega-3 and its derivatives (18; 3n-3; ALA) rich in flaxseeds and relieves symptoms of dry-eye. Therefore, the purpose of this study is to summarize the scientific-based evidence on the role of polyunsaturated fatty acid derivative flaxseed in the treatment of patients suffering from dry eye syndrome. Methodology: The database collected from PubMed, PubMed Central (PMC), Cochrane library, Google scholar and research gate. Discussion and Conclusion: At present, there are varieties of buffered formulations containing electrolytes, surfactants, preservatives available in the market that aggravate the patient__ampersandsignrsquo;s symptoms (tear film instability, poor epithelial healing) due to reported cytotoxicity. The nutraceutical, preservative-free supplements are, therefore, better alternatives for managing conjunctival dryness. The limited evidence and researches on flaxseed suggest standardized, well-designed Randomized Control Trials for delivering an accurate dose recommendation for dry eye patients.