Cancer is one of the most perplexing diseases which have been plaguing worldwide and had been accounted for 8.2 million of all deaths in 2012 as reported by World Health Organization (WHO) in 2014.According to WHO, it is the second leading cause of death in the developing countries after cardiovascular diseases. American Cancer Society defines it as __ampersandsignldquo;a large group of diseases, all characterized by uncontrolled growth and spread of abnormal cells__ampersandsignrdquo;. Its etiology is still not completely understood but certain dietary factors and environmental agents act on the genetic material in cells leading to the chemical changes that may initiate the progression of abnormal cell mass. The Sartan (cancer) is well described in the Unani Classical Medical Literature as __ampersandsignldquo;Sartan__ampersandsignrdquo; or __ampersandsignldquo;Warm-e-Sulb-Saudavi__ampersandsignrdquo;. While going through the literature review of various compendiums written by Unani physicians, it is clear that this system of medicine had vast knowledge about sartan. In spite of the present advanced treatment options there is no effective and satisfactory treatment for cancer. The treatment besides being very expensive, are associated with serious side effects and morbidity due to their toxic effects. The search still continues for a treatment that has minimal side effects and is cost effective. Unani medicine has produced many useful leads in developing medications for chronic systemic diseases as proved by numerous clinical trials. Therefore, a Unani alternative approach is being explored in the light of classical Unani literature for the management of Sartan as a safe and efficacious treatment option. The role of Munzij and Mus__ampersandsignrsquo;hil therapy, which isan important part of Ilaj bit Tadbeer (Regimenal therapy)in treating such disorders, is well recognized in Unani classical literature.