Background: Weighing the child at regular intervals allows parents and pediatricians to see weight fluctuations and give guidance to the mother based on this weight change. Aim: To determine the effectiveness of Structured Teaching Programme (STP) on the knowledge and practice regarding growth monitoring among the Anganwadi workers. Methods: A pre-experimental pre-test, the post-test research design was used to conduct this study with convenience sampling to collect data from 60 Anganwadi workers using structured questionnaire. After collecting pre-test data, STP was organized for the intervention of growth monitoring to samples. Seven days were provided to the samples for utilizing STP which was organized for 45-50 minutes through lecture, discussion and planned Audio-Visual (AV) aids. Post-test information was gathered after seven days from the Seven days was assigned after getting expert opinions as well as to give time for the implication of knowledge through the practice of growth monitoring with the help of an observational checklist. The sample characteristics were described by frequency, percentage and t-test were used to describe the difference between pre-test and post-test knowledge score. Results: The Mean Pre-test knowledge score of the Anganwadi workers in the pre-test was 10.40 __ampersandsignplusmn; 1.86 and in post-test, it was 18.03__ampersandsignplusmn;1.10.Among 65% of Anganwadi workers had a very good level of practice score and 35% had an excellent level of practice score. Mean practice score of the Anganwadi workers was 12.26__ampersandsignplusmn; 1.20 and mean percentage score was 81.77__ampersandsignplusmn;8.03. Conclusion: It is important to give health education and teaching to the Anganwadi workers to improve the skills and upgradation of the new knowledge.