Introduction: Respiratory diseases today are one of the urgent problems of paediatrics and occupy the first place in the structure of child morbidity and mortality. Objective: The study aimed to identify the main risk factors for the development of broncho-obstructive syndrome in young children based on the data of the Samarkand Branch of the Republican Scientific Center for Emergency Medical Aid. Methods: Assessment of risk factors for the development of broncho-obstructive syndrome was carried out using statistical methods in epidemiological analysis. We carried out a retrospective analysis of 912 case histories of children with the bronchoobstructive syndrome at the age of 1 to 3 years. General analysis of blood, urine, faeces, X-ray examinations of the chest organs, pulse oximetry data and expert opinions. Result: Biofeedback developed against the background of acute obstructive bronchitis was diagnosed in 494 (54.2%) children as compared to 418 (45.8%) patients in other group. Studies have shown that risk factors are cases of exudative forms of atopic dermatitis (39.1%), lymphatic-hypoplastic diathesis (19.5%), prematurity 61 (9.4%), with acute obstructive bronchitis -46, and with acute bronchitis - 15 children. Disharmonious physical development was noted (in 223 children, 36.4%) due to an increase in body weight above the 90th percentile. Conclusion: Main risk factors for the development of broncho-obstructive syndrome are children over a year old, winter and spring seasons of the year, perinatal encephalopathy, aggravated allergic anamnesis, protein-energy malnutrition, part trophy, food allergy, early transfer of children to artificial feeding, hereditary and congenital pathology of the bronchopulmonary system and others. All this dictates the need for preventive work in families and family clinics for the prevention of bronchial asthma in the future.