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<article xlink="http://www.w3.org/1999/xlink" dtd-version="1.0" article-type="healthcare" lang="en"><front><journal-meta><journal-id journal-id-type="publisher">IJCRR</journal-id><journal-id journal-id-type="nlm-ta">I Journ Cur Res Re</journal-id><journal-title-group><journal-title>International Journal of Current Research and Review</journal-title><abbrev-journal-title abbrev-type="pubmed">I Journ Cur Res Re</abbrev-journal-title></journal-title-group><issn pub-type="ppub">2231-2196</issn><issn pub-type="opub">0975-5241</issn><publisher><publisher-name>Radiance Research Academy</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">3122</article-id><article-id pub-id-type="doi"/><article-id pub-id-type="doi-url"> http://dx.doi.org/10.31782/IJCRR.2020.SP90</article-id><article-categories><subj-group subj-group-type="heading"><subject>Healthcare</subject></subj-group></article-categories><title-group><article-title>Evaluation of Postoperative Analgesia Using Clonidine as an Adjuvant with Caudal Bupivacaine in Paediatric Patients Posted for Infraumbilical Surgery&#13;
</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Agarwal</surname><given-names>Sinjini</given-names></name></contrib><contrib contrib-type="author"><name><surname>(Verma)</surname><given-names>Neeta Chaudhary</given-names></name></contrib><contrib contrib-type="author"><name><surname>Singam</surname><given-names>Amol</given-names></name></contrib><contrib contrib-type="author"><name><surname>Singh</surname><given-names>Kavita</given-names></name></contrib></contrib-group><pub-date pub-type="ppub"><day>30</day><month>11</month><year>2020</year></pub-date><volume>mi</volume><issue>ic</issue><fpage>38</fpage><lpage>42</lpage><permissions><copyright-statement>This article is copyright of Popeye Publishing, 2009</copyright-statement><copyright-year>2009</copyright-year><license license-type="open-access" href="http://creativecommons.org/licenses/by/4.0/"><license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.</license-p></license></permissions><abstract><p>Introduction: Caudal block epidurally is a highly popular means of administering pain relief to children undergoing infra-umbilical surgeries. Addition of clonidine, a centrally acting alpha 2 agonist as an adjuvant to caudal Bupicaine has added advantages of providing prolonged postoperative analgesia and also, thus reducing the no. of doses of postoperative rescue pain relief agents. Objective: To compare the efficacy and safety of caudally administered clonidine as an adjuvant to bupivacaine. Methods: The study will be carried out with 40 patients in each group randomly allocated using computer-generated software, posted for infraumbilical surgeries between the age group 2 years to 7 years, ASA grade I and II. Children less than 2 yrs or more than 7 yrs, ASA grade III-IV, in case of any allergy to drugs involved in this study, serious cardiac or respiratory disease, history of developmental delay or mental retardation, caudal block site infection if present, then it will be excluded from the study. Group B (control group) Caudal epidural with 0.25% bupivacaine 1 ml/kg +1 ml Normal saline (NS) Group C (study group) Caudal epidural with 0.25% bupivacaine 1ml/kg with clonidine 1 ug/kg+1ml Results: It is expected that the duration and quality of postoperative analgesia in group C will be prolonged as compared to that in group B. Haemodynamic changes with no significant difference between the 2 groups are expected. Also minimal or no adverse effects are anticipated. Conclusion: We expect to conclude that caudally administered clonidine, in a dose of one microgram /kg as an adjuvant to 0.25% bupivacaine 1 ml/kg, will prove to be efficacious in providing prolonged analgesia both intraoperatively and postoperatively. Also, we hope that this addition reduces the requirement of postoperative rescue analgesia and its associated side effects.&#13;
</p></abstract><kwd-group><kwd> Caudal block</kwd><kwd> Neuraxial block</kwd><kwd> Caudal epidural</kwd></kwd-group></article-meta></front></article>
