IJCRRI Journ Cur Res ReInternational Journal of Current Research and ReviewI Journ Cur Res Re2231-21960975-5241Radiance Research Academy3089http://dx.doi.org/10.31782/IJCRR.2020.12225HealthcareIncidence of Mupirocin Resistance in Staphylococcus Aureus Isolated from Rural Population: A New Emerging Challenge KumarDineshBishtDakshinaFaujdarSameer Singh241120202)8285This article is copyright of Popeye Publishing, 20092009This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.

Introduction: Staphylococcus aureus is the most common bacteria linked to disease and death, causing serious communityacquired and nosocomial infections. Therefore mupirocin has been frequently used for treatment Staphylococcus aureus infections. Aim: This research was conducted to evaluate the prevalence of mupirocin (Mup) resistance in our tertiary care hospital. Methods: All strains of S. aureus were isolated from various clinical samples from patients either attending the outdoor services or getting treatment in the hospital. Detection of Mup-resistant Staphylococcus aureus was done by disc diffusion and E-test methods. Results: Overall 265 S. aureus was obtained from numerous clinical samples. Among these, 111 isolates (42%) were MRSA. The overall occurrence of mupirocin resistance was 13% among all S. aureus isolates. Mupirocin resistance was found 19% in MRSA and 09% in MSSA. Conclusion: Mupirocin resistance can be reduced by proper use of mupirocin and conducting regular tests to manage S. aureus colonization among health care workers.

Mupirocin resistance High-level Low-level Staphylococcus aureus Methicillin-Resistant S. aureus (MRSA) methicillin-susceptible S. aureus (MSSA)