Background: Ultrasonography (USG) in today__ampersandsignrsquo;s scenario is extremely crucial for detection of the dimensions of the tumour, for the diagnosis of multinodular goitres, and more importantly the nature of the solitary thyroid nodule whether it is solid or cystic. Very rarely cystic nodule is associated with malignancy. Aims __ampersandsignamp; Objectives: Our study on solitary thyroid nodules will try to corroborate the pre-operative cytological diagnosis obtained by USG guided Fine Needle Aspiration Cytology with the postoperative histopathological diagnosis. Methods: We have studied 60 patients taken from a tertiary care hospital for one year. We have considered to only the patients with solitary thyroid nodule of both sexes and all age groups. The type of operation was planned as per the report of USG guided fine needle aspiration cytology (FNAC). Results: Patients were aged between 15-75 years. 83 % of the patients in our study were females. Commonly associated symptoms were of hoarseness of voice, lymph node involvement __ampersandsignamp; those nodes are fixed to the underlying structures __ampersandsignamp; all these symptoms strongly suggestive of malignancy. Conclusion: When properly done by an expert cytopathologist, we can reliably diagnose the benign cases, that can be managed reasonably by conservative approach rather than subjecting all patients to operations.