Introduction: As an infectious disease, COVID-19 is successfully being contained globally by instituting widespread quarantine measures. The 2019 Novel Coronavirus disease (COVID-19) epidemic is a public health emergency of international concern and poses a challenge to the psychological resilience, economy, and social life of people. Research data are needed to develop evidence-driven strategies to reduce adverse psychological impacts, economic recession, and disturbance of social life during the epidemic. The main aim of the study was to assess the psychological impact and effects due to COVID-19 among the general population. Material and Methods: A self-administered questionnaire was prepared to analyze the psychological impact of quarantine on the individuals during this period. A cross-sectional study was conducted in a sample of 100 individuals and data was collected and analyzed using SPSS software. Chi-square test was done and a P-value of __ampersandsignlt; 0.05 was said to be statistically significant. Result and Discussion: 71.3% of the respondents have heard of the term COVID-19 while 28.7% of the respondents have not heard. 52.5% of the respondents were under stress during this period while 47.5% of the respondents were not under any stress during this period. Conclusion: Hence, the study shows us that 70% of the respondents__ampersandsign#39; mental health was affected during this period.