Background: A lot of studies have shown the immediate effect of Bhramari pranayama on cardiovascular parameters in healthy individuals but to the best of our knowledge none have been done on the hypertensive patients Aim: This study aimed to determine the immediate effects of Bhramari pranayama on hypertensive patients in terms of Systolic and Diastolic Blood pressure, Heart rate and oxygen saturation (SpO2) Methods: Total of 40 participants meeting the inclusion criteria were included in the study. The participants were randomly divided into two groups experimental (Bhramari pranayama) and the control group of 20 each. The experimental group performed the Bhramari pranayama for 5 minutes. The control group did not receive any treatment. Pre and immediate post-intervention scores were measured in terms of systolic BP, Diastolic BP, heart rate and SpO2. Result: On comparing the pre and post-intervention values of the outcome measures, it was observed that there was a statistically significant difference in Systolic BP values in Bhramari pranayama group. No significant difference was seen in Pre and Post values of Systolic and Diastolic BP, Heart rate and SpO2 values in Control group. On comparing between the groups, it was observed that there was no statistically significant difference between the two groups in terms of systolic BP, Diastolic BP, heart rate and SpO2 Conclusion: Based on the present study, it can be concluded that the Bhramari pranayama has an immediate positive effect on reducing the Systolic Blood pressure acting through parasympathetic dominance. It can be practised in daily routine to reduce the stress originated cardiovascular risk in future.