Introduction: Three Dimensional (3D) printing was a daydream for various researchers and scientists. But now in today__ampersandsignrsquo;s era, this dream comes into reality. 3D printing is a rapidly growing technique in this era. Objective: The objective of this review was to describe advanced applications of 3D printing in the biomedical field. Methods: The methodology involves the critical review of the topic through different authentic scientific sources such as ScienceDirect, Pubmed, Google Scholar, etc. with the help of appropriate keywords. Results: 3D system provide opportunities to medical and pharmaceutical industries to design more specific and authentic drug delivery system, high productivity of surgical and implants, more pr__ampersandsigneacute;cised and personalized health care system and it is also helpful to save the life of people due to any organ failure or damage in case of any accidents or diseases. 3D printing is used to generate models, devices, surgical tools, delivery system, implants, and prostheses. Conclusion: 3D printing has great potential for future use in the biomedical field. In future, 3D printing will bring a revolution in the health care system.