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<article xlink="http://www.w3.org/1999/xlink" dtd-version="1.0" article-type="healthcare" lang="en"><front><journal-meta><journal-id journal-id-type="publisher">IJCRR</journal-id><journal-id journal-id-type="nlm-ta">I Journ Cur Res Re</journal-id><journal-title-group><journal-title>International Journal of Current Research and Review</journal-title><abbrev-journal-title abbrev-type="pubmed">I Journ Cur Res Re</abbrev-journal-title></journal-title-group><issn pub-type="ppub">2231-2196</issn><issn pub-type="opub">0975-5241</issn><publisher><publisher-name>Radiance Research Academy</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">2896</article-id><article-id pub-id-type="doi"/><article-id pub-id-type="doi-url"> http://dx.doi.org/10.31782/IJCRR.2020.121811</article-id><article-categories><subj-group subj-group-type="heading"><subject>Healthcare</subject></subj-group></article-categories><title-group><article-title>Comparison of 0.5% Hyperbaric Bupivacaine Versus 1% Chloroprocaine in Spinal Anaesthesia in an Ambulatory Setting; a Randomized DoubleBlind Interventional Study&#13;
</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Kalra</surname><given-names>Poonam</given-names></name></contrib><contrib contrib-type="author"><name><surname>Jain</surname><given-names>Priyanka</given-names></name></contrib><contrib contrib-type="author"><name><surname>Sharma</surname><given-names>Piyush</given-names></name></contrib><contrib contrib-type="author"><name><surname>Poddar</surname><given-names>Ravindra</given-names></name></contrib></contrib-group><pub-date pub-type="ppub"><day>22</day><month>09</month><year>2020</year></pub-date><volume>8)</volume><issue/><fpage>73</fpage><lpage>79</lpage><permissions><copyright-statement>This article is copyright of Popeye Publishing, 2009</copyright-statement><copyright-year>2009</copyright-year><license license-type="open-access" href="http://creativecommons.org/licenses/by/4.0/"><license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.</license-p></license></permissions><abstract><p>The choice of ideal local anaesthetic agent for spinal anaesthesia is therefore crucial in the ambulatory setting. Lignocaine is associated with a high incidence of transient neurological symptoms, and bupivacaine produces sensory and motor blocks for a prolonged duration. Aims: This study was designed to compare preservative-free 2-chloroprocaine 40 mg with hyperbaric bupivacaine 15 mg for spinal anaesthesia in an elective ambulatory setting. Methodology: After approval from the institutional ethics committee, this prospective double-blind interventional study was conducted in 64 patients undergoing spinal anaesthesia. Informed consent was obtained and the study sample was divided into two groups. Group A-1%2-chloroprocaine(n=32), Group B-0.5% hyperbaric bupivacaine(n=32).For statistical analysis, unpaired T-test and chi-square test were used. Results: The onset characteristics of the sensory block were similar between the groups. However, the onset of motor block, regression characteristics did show a different profile between the two groups. The time for complete regression of sensory blockade to S2 in the 2-CP group was less that of the bupivacaine group (147 min vs 252 min, respectively, p value__ampersandsignlt;0.0001), a difference of 95 minutes. Similarly, the duration of the motor __ampersandsignamp; sensory block was significantly shorter in the chloroprocaine group. The time for ambulation was 184 minutes in chloroprocaine group compared to 280 minutes in the bupivacaine group(p value__ampersandsignlt;0.0001). Conclusions: 40 mg of plain 1% 2-chloroprocaine proved to be comparable with 15 mg of 0.5% hyperbaric bupivacaine in terms of onset of sensory block. But showed faster recovery from anaesthesia implying superior suitability for outpatient surgeries.&#13;
</p></abstract><kwd-group><kwd> Infra-umbilical surgeries</kwd><kwd> 2-chloroprocaine</kwd><kwd> Bupivacaine</kwd><kwd> Spinal Anaesthesia</kwd><kwd> Sensory Block</kwd><kwd> Motor Block</kwd></kwd-group></article-meta></front></article>
