Introduction: Disease can emerge from any tissue in the body. Tissues with quickly duplicating cells are at more danger of having the disease. The haemopoietic framework is one of them. Aim: The present study aims at knowing the break up of haematological malignancies, they are the clinico-haematological correlation; classify them by adapting the FAB classification and providing study based suggestions for better diagnosis and treatment of haematological malignancies Methods-In the present study, a total of ninety-eight cases of haematological malignancies were studied to evaluate the clinico-haematological spectrum of different types of haematological malignancies. Patients belonged to all age groups, the youngest being 1 year old and the eldest 86 years. Results: Majority of cases were seen in 5th-7th decades. Majority of cases of ALL were below 20 years of age while AML was seen in all age groups. CML was commonly found in middle age whereas CLL was seen in the elderly. The male: female ratio was 2.92: 1. Common clinical signs included pallor, splenomegaly and/or hepatomegaly. In CML, weakness, abdominal fullness and pain, and fever were the common presenting feature whereas; splenomegaly was present in the majority of the cases. In laboratory investigations, the majority of cases of AML and ALL had severe anaemia (Hb __ampersandsignlt;7gm. The total leukocyte count was raised in the majority of cases of AML while for ALL, the TLC varied from leucocytosis to severe leucopenia (1, 100-3, 20, 000/ cmm). All the cases of AML had thrombocytopenia (mean 36,785/cmm), while the majority of cases of ALL also had decreased platelet count. Majority of cases of CML had thrombocytosis. Conclusion: More studies are required on larger samples and with the help of more sophisticated diagnostic techniques to have a better idea of different subtypes of the individual malignancies and to achieve better therapeutic goals in this area. No doubt this is tedious work, but it is not impossible if a little attention is paid to this important health problem.