Introduction: This is a case-control study comparing various lung function indices suggestive of OAD amongst the patients with ischemic heart disease and /or hypertension and healthy control population without ischemic heart disease and/or hypertension. Methods: In present study total of 100 subjects are cases, which include subjects with hypertension and / or ischemic heart disease. Results: Out of total 100 cases, 34 are IHD 37 are with essential hypertension and 29 are with IHD and Hypertension. In case population total 59 subjects are male (IHD,HTN: 18; IHD:23 ; HTN: 18) and 41 subjects are female (IHD,HTN: 12; IHD:11; HTN: 18). In control group total 74 are male and 26 are female Descriptive Statistical analysis for case group in following table number 3 shows mean values of age: 53.24, SBP: 157, DBP: 90.74, FEV1:1.531, FVC: 1.897, FEV1/FVC ratio %: 80.95, FEF 25-75:1.684, PEFR: 3.6, BMI: 22.71 Kg/m2. Out of a total of 37 hypertensive patients, 8 are having (21.62 % (OR=23.31) 95% confidence interval) OAD. Out of a total 34 IHD patients, 6 are having (17.34 % (OR=21.21) 95% confidence interval) OAD. Out of total 29 IHD with hypertensive patients, 4 are having (13.79 % (OR=15.84) 95% confidence interval) OAD. The mean FEV1/ FVC (%) in the male population is significantly low (58.396) compared to the female population (64.670) amongst the case group (p__ampersandsignlt; 0.001). The mean SBP and DBP is significantly high in female population (163.333; 100.667) compared to male population (152.667; 89.600) with p __ampersandsignlt; 0.05. Conclusion: The use of FEV1 and FEV1/FVC % as the part cost-effective investigation of any health assessment of middleaged patients should be considered. Patients with IHD and hypertension should routinely undergo inexpensive investigation like spirometry to detect the presence of underlying asymptomatic or subclinical OAD.