Introduction: Proliferative diabetic retinopathy (PDR), characterized by neovascularization either at the optic disc (NVD) or elsewhere (NVE), may be associated with clinically significant macular oedema (CSME) or cystoid macular oedema (CME). Tractional retinal detachment in PDR is the result of neovascularization. As conventional management of PDR may not always prove effective, alternative options, including Ayurvedic treatment protocols, may be sought. Case Series: 3 diagnosed cases of PDR with associated conditions were managed using specially tailored Ayurvedic oral medicines, external therapies for both the eyes and head and a dietary protocol at Sreedhareeyam Ayurvedic Eye Hospital and Research Center, India. Both ocular and systemic parameters showed improvement at discharge. Discussion: The patients__ampersandsignrsquo; symptoms were compared to Timira or blurring of vision. Diagnostic parameters in Ayurveda were explored along the lines of pathological activity of Tridoshas (three somatic senses of humour - Vata, Pitta, and Kapha) and Rakta (blood tissue). Treatments were aimed not only at PDR and its complications, but also to normalize digestion and metabolism, thus revitalizing normal physiology. This holistic approach can make Ayurvedic management of PDR an option to consider..