Introduction: Nowadays, all over the world, a trend of steady growth in oncological diseases is increasing. This article highlights some problems of onco-psychology and provides an experimental analysis of the characteristics of the disease response and the assessment of the social status of their sickness in patients diagnosed with the oncological illness. Aim and Objective: The study of women__ampersandsignrsquo;s attitudes towards the disease in patients treated for breast cancer is important in activities aimed at improving the patient__ampersandsignrsquo;s various pain and quality of life. Method: The study involved 62 female patients diagnosed with breast cancer treated at the Republican Specialized ScientificPractical Medical Center of Oncology and Radiology. The __ampersandsignldquo;Serdyuk__ampersandsignrdquo; questionnaire was used to assess the social status of the disease in patients. Result: According to the results of the conducted study, the indicators on the assessment of the personal and social status of patients on all scales of the test increased from the bottom up in the stages of the disease. That is, as the stages of the disease progress, they have felt weak, powerless, experienced changes in family relationships, increased tendency to depression, subdepression and depression, decreased leisure time, increased time spent mainly on treatment. Conclusion: Hospitalization, limited opportunities to improve professional status in society, and as well patients are concerned about looking ugly and unattractive to those around them, especially their spouse, are mentally unwilling, have increased feelings of weakness, felt limited in communication, and experienced economic hardship.