Background: Appendicitis is one of the most usual abdominal conditions requiring urgent surgical intervention. The current study was done to discover diverse appendicular histopathological lesions, their statistics and the percentage of a ruptured appendix, incidental appendectomy and negative appendectomy. Type of study: Retrospective cross-sectional study. Materials and Methods: Resected samples of appendices were given to histopathology Department of Pathology Chandulal Chandrakar Memorial Medical College and hospital. Results: Out of 1180 samples of the appendix, appendicitis accounted for 90.68% with peak age incidence in the age group of 15 to 25 yrs in both genders. Histopathological diagnoses of different types of appendicitis included acute (49.06%), acute suppurative (22.06%), gangrenous (17.66%), perforated (3.64%), resolving/ recurrent chronic (2.90%), acute eosinophilic (3.46%), xantho-granulomatous (0.84%), and carcinoid tumcurrent (0.37%). Other important accompanying pathologies were parasitic infestation and Meckel__ampersandsignrsquo;s diverticulosis. Negative appendectomy rate was 7.8% which was much more common in females. Conclusion: Incidence of appendicitis is higher in adolescents and young adults and slightly higher in females. Negative appendectomy is also very common in females. Last but not the least, an unusual finding such as carcinoid tumour in the clinically suspected acute appendicitis reflects the value of histological examination of every resected appendix and its presence would change the currents of further management.