Breast carcinoma is known to be one of the commonest malignant tumours among which Axillary breast cancer is a special individual that accounts for 0.1% to 2% of all cases of breast cancer. This is usually composed of poorly differentiated IDC with squamous or mesenchymal carcinoma areas sometimes. Axillary malignancy is difficult as there are many differential diagnoses that may require careful evaluation. This is a case report on Breast carcinoma of tail of Spence in axilla with skin involvement near nipple-areola complex whose histopathology was suggestive of infiltrating ductal carcinoma of axillary tail of Spence with mild dysplastic changes over right nipple-areola complex and high lymph node positivity (96.7%). Standard investigations like Ultrasonography of B/L Breast with Axilla and Tru-cut biopsy were done to reach the diagnosis of Intraductal Carcinoma (IDC) of the axillary tail.