Introduction: The thyroid organ is a butterfly-model organ made out of globular right and left flaps associated in the midline by a meagre organisation named isthmus. Disorder related to thyroid consists of a group of disease of endocrines. All of these disorders may be associated with clinical conditions of hyper as well as hypo thyroids. Surgical excision and pathological evaluation are vital to establish a proper diagnosis. Aim: The study to show the histopathological forms of thyroid lesions observed in a tertiary care hospital. Materials and Methods: The present cross-sectional study was conducted for 2 years. Inclusion criteria: The test population included patients with thyroid pathology in a specified period. Thyroidectomy specimens including lobectomy, partial thyroidectomy, subtotal thyroidectomy and total thyroidectomy. Exclusion criteria: Patients with other disorder than thyroid were excluded. Results: The total number of studied cases was 225 cases (table 1). The reviewed cases were classically categorized into two main groups; Non- neoplastic (132; 58.5%) and Neoplastic (93; 41.5%). Papillary carcinoma was the most frequent thyroid cancer accounting for most of the thyroid cancers. Conclusion: Thus, in conclusion, females accounted for a higher number of patients with neoplastic thyroid lesions and the prevalence peaked at a younger age. Present study finding suggests that papillary carcinoma appears much before development so diagnosis should be fastened.