Aim: The objective of this study was to evaluate the effects of cumulative partial sleep deprivation (i.e. restricted sleep __ampersandsignlt;6 hours a night for 3-4 consecutive nights) on various aspects of Neurocognitive functions in female nursing students. Methodology: Pittsburgh Quality of Sleep Index (PQSI) scoring and neurocognitive tests viz. Letter cancellation test (LCT), Trail making tests A and B and Forward and Backward digit span tests were performed in 30 apparently healthy female nursing students. The students, who slept for a minimum of 7 hours / day for at least three consecutive nights, were selected for baseline assessment during their non-sleep deprived phase. Repeat evaluation was performed when the sleep duration was __ampersandsignlt;6 hours / day for at least three consecutive nights in their sleep-deprived phase. Result: The study demonstrated a significant increase in PQSI scores (p=0.0.0001***), Letter cancellation test time duration (p=0.0022**), LCT errors (p=0.0109*), Trail making tests A and B time duration (p=0.0048**, p=0.0001*** respectively) and a significant decrease in Backward digit span test score (p=0.0135*) during sleep-deprived phase as compared to non-sleep deprived phase. No significant change was observed in the Forward digit span test (p=0.3097). No statistically significant association was obtained between the PSQI score and the various neurocognitive tests. Conclusion: Chronic Partial sleep deprivation deteriorates neurocognitive function viz; visual scanning, response speed, sustained attention, executive function, and working memory as demonstrated by significant changes in various neurocognitive tests.