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<article xlink="http://www.w3.org/1999/xlink" dtd-version="1.0" article-type="healthcare" lang="en"><front><journal-meta><journal-id journal-id-type="publisher">IJCRR</journal-id><journal-id journal-id-type="nlm-ta">I Journ Cur Res Re</journal-id><journal-title-group><journal-title>International Journal of Current Research and Review</journal-title><abbrev-journal-title abbrev-type="pubmed">I Journ Cur Res Re</abbrev-journal-title></journal-title-group><issn pub-type="ppub">2231-2196</issn><issn pub-type="opub">0975-5241</issn><publisher><publisher-name>Radiance Research Academy</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">2700</article-id><article-id pub-id-type="doi"/><article-id pub-id-type="doi-url">http://dx.doi.org/10.31782/IJCRR.2020.12136</article-id><article-categories><subj-group subj-group-type="heading"><subject>Healthcare</subject></subj-group></article-categories><title-group><article-title>Pathophysiologic Enigma of COVID-19 Pandemic with Clinical Correlates&#13;
</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Parveen</surname><given-names>Sana</given-names></name></contrib><contrib contrib-type="author"><name><surname>Jain</surname><given-names>Shraddha</given-names></name></contrib></contrib-group><pub-date pub-type="ppub"><day>6</day><month>07</month><year>2020</year></pub-date><volume>3)</volume><issue/><fpage>33</fpage><lpage>37</lpage><permissions><copyright-statement>This article is copyright of Popeye Publishing, 2009</copyright-statement><copyright-year>2009</copyright-year><license license-type="open-access" href="http://creativecommons.org/licenses/by/4.0/"><license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.</license-p></license></permissions><abstract><p>Introduction: This review article examines the virology, modes of transmission, risk factors, clinical course, diagnosis and treatment of Coronavirus disease based on the various studies done in the past 8 months.&#13;
Background: Covid-19(Coronavirus disease 2019) has been named as a novel virus as there has been no known cases of infection with this strain in human beings. Origin of this virus is alleged to be from a family of bats and pangolins, in Wuhan, China in Dec 2019 from a seafood market, and since then the spread of this virus has been unstoppable.After a single introduction into the human population, the Chinese authorities immediately notified the WHO about the increasing number of COVID -19 cases. An epidemic was caused due to the SARS virus in China in 2003, and hence this virus has been renamed as SARS-Cov-2 because of its close relation to it. The symptoms of this disease can vary from mild flu-like to severe respiratory distress requiring admission to ICU.&#13;
Methods: The literature on COVID-19 was retrieved from PubMed, Google Scholar and Cochrane database. Keywords and phrases used during the search included __ampersandsignldquo;Covid-19,__ampersandsignrdquo; __ampersandsignldquo;pandemic,__ampersandsignrdquo; __ampersandsignldquo;Novel__ampersandsignrdquo; and __ampersandsignldquo;Coronavirus__ampersandsignrdquo;.&#13;
Conclusion: At present, no definitive treatment is available for this virus; only symptomatic management is undertaken. Further research is being undertaken to develop the Coronavirus vaccine and the use of plasma of treated patients to manage active infected cases.&#13;
</p></abstract><kwd-group><kwd>COVID</kwd><kwd> Pandemic</kwd><kwd> Seafood</kwd><kwd> Recombination</kwd><kwd> Zoonotic spillover</kwd></kwd-group></article-meta></front></article>
