Meningoencephalitis is a very critical illness that is widespread andit remains a major cause of mortality and morbidity with neurological disabilities. It usually presents with varying degrees of symptoms of meningeal inflammation, posing difficulties in diagnosis and treatment. Study was conducted to Evaluate clinical severity and CSF(cerebrospinal fluid) findings at presentation. Encompassing the clinical status, CSF assays, along with revelations of recent trends of infection responsible formeningoencephalitis, this study also shows that early confirmation of clinical suspicion with judgement of severity __ampersandsignamp; CSF study, is of great significance. Prompt diagnosis providesphysicians with an opportunity to prevent undue mortality and morbidity.. Here lies therelevance of this study.