Introduction: Prevalence of RTIs in females are very high and vary widely country to country and also region. Aim: The present study was aimed to look distribution of common RTIs in symptomatic females attending obstetrics and gynaecology OPD of a rural tertiary care hospital in Central India. Methods: Four high vaginal swabs and blood for serum was collected from each patient. Sample were processed for wet mount, gram stain, culture,VDRL and Mod. TPHA. Results: 500 females __ampersandsignnbsp;were screened for presence of symptoms of RTIs and 33.4% (167/500) had one or the other symptoms of RTIs. Candidiasis (25.14%) including non albicans candida and Bacterial vaginosis (23.95%) __ampersandsignnbsp;were the most prevalent infections followed by Trichomonas vaginalis __ampersandsignnbsp;12/167 (7.1%) and syphilis 3/167 (1.7%). Conclusion: We observed laboratory confirmed predominance of candidiasis and BV in both urban and rural population and in pregnant as well as non pregnant females. Presence of considerable amount of infections in pregnant females calls for a routine screening of RTIs in this group. Also, clinically diagnosed Candida infection should be confirmed to species level as the NAC are more resistant to treatment leading to recurrent Vulvovaginal candidiasis.__ampersandsignnbsp;