Introduction: Advancement of technology has affected the surgical methods of tonsillectomy for reaching desired benefits. This study aims to find a practical, economical and pragmatic way in managing post-operative morbidity with respect to tonsillectomy. Materials and Methods: Patients were randomly divided into two groups __ampersandsignndash; Group A and Group B. Group A received Injectiondexamethasone, while Group B received oral pantoprazole. Post-operatively patients were assessed on pain, incidence of haemorrhage and wound healing on POD 0, 1, 7 and 14. Results: Group A had comparatively less pain on POD 0 and POD 1, but over the long term both groups didn__ampersandsignrsquo;t show any significant difference. Both groups didn__ampersandsignrsquo;t show much difference in regards to healing of tonsillar fossa. Incidence of Secondary haemorrhage (2%) and Reactionary haemorrhage (4%) were seen in Group A, but no incidence of haemorrhage was recorded in Group B. Discussion: Tonsillectomy as a surgical procedurehas evolved over the years.our study tookin to account two pharmacological agents which is administered,works and acts by radically different approach in which most potent,economical with fewer side effect was found to be Dexamethasone. Conclusion: The results concluded that there was no significant statistical difference between the two drugs in alleviating postoperative pain, haemorrhage and wound healing.__ampersandsignnbsp;