__ampersandsignnbsp;Objective: Usually, the stratospheric ozone will show its significance in the variability of mesospheric tides in normal days over the low-latitude region. But during sudden stratosphere warmings, the water vapor and ozone over the polar region will change and shows some different effects on mesosphere tides. In the present study, we have provided the unusual changes in both water vapor and ozone over Antarctica and their role in altering the mesospheric tides. Method:__ampersandsignnbsp;Using MLS data in the stratosphere and Rothera (68oS, 68oW)__ampersandsignnbsp;MF radar observations in the mesosphere, the variability of Antarctica ozone and H2O during sudden stratospheric warming (SSW)__ampersandsignnbsp;winter 2010, and their influence on mesosphere dynamics has presented. The unusual increment of ozone reduction is noticed and consequent enhancement in H2O and HNO3 is also observed during the warming period. Mesospheric tidal components (diurnal, semi-diurnal and terr-diurnal)__ampersandsignnbsp;have been estimated using the hourly wind data from the MF radar. Result:__ampersandsignnbsp;The unusual changes in H2O and Ozone were observed during the warming period the similar behavior was observed in semi-diurnal tidal components during 2010 winter and their relation to ozone enhancement is discussed. Conclusion:__ampersandsignnbsp;The observations indicate that the enhancement of H2O and HNO3 leads to produce the ozone during warming period and hence the increment in ozone reduction is achieved over the polar region. Further, the enhancement of Brewer-__ampersandsignnbsp;Dobson mean circulation was clearly noticed through ozone transport during the warming period. The tidal enhancement after the SSW could be due to the non-linear interaction between planetary waves and tides.