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<article xlink="http://www.w3.org/1999/xlink" dtd-version="1.0" article-type="healthcare" lang="en"><front><journal-meta><journal-id journal-id-type="publisher">IJCRR</journal-id><journal-id journal-id-type="nlm-ta">I Journ Cur Res Re</journal-id><journal-title-group><journal-title>International Journal of Current Research and Review</journal-title><abbrev-journal-title abbrev-type="pubmed">I Journ Cur Res Re</abbrev-journal-title></journal-title-group><issn pub-type="ppub">2231-2196</issn><issn pub-type="opub">0975-5241</issn><publisher><publisher-name>Radiance Research Academy</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">2487</article-id><article-id pub-id-type="doi"/><article-id pub-id-type="doi-url">http://dx.doi.org/10.31782/IJCRR.2018.10103</article-id><article-categories><subj-group subj-group-type="heading"><subject>Healthcare</subject></subj-group></article-categories><title-group><article-title>Demographic, Clinical and Etiological Profile of Young Dystonia Less Than Forty Years of Age __ampersandsignndash; A Hospital Based Study&#13;
</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Ahmad</surname><given-names>S. Bashir</given-names></name></contrib><contrib contrib-type="author"><name><surname>Z.</surname><given-names>Bashir</given-names></name></contrib><contrib contrib-type="author"><name><surname>S.</surname><given-names>Tak</given-names></name></contrib><contrib contrib-type="author"><name><surname>V.</surname><given-names>Goyal</given-names></name></contrib><contrib contrib-type="author"><name><surname>M.</surname><given-names>Behari</given-names></name></contrib></contrib-group><pub-date pub-type="ppub"><day>30</day><month>05</month><year>2018</year></pub-date><volume>0)</volume><issue/><fpage>19</fpage><lpage>26</lpage><permissions><copyright-statement>This article is copyright of Popeye Publishing, 2009</copyright-statement><copyright-year>2009</copyright-year><license license-type="open-access" href="http://creativecommons.org/licenses/by/4.0/"><license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.</license-p></license></permissions><abstract><p>Objective:__ampersandsignnbsp;To study the demographic, clinical and etiological profile of dystonia in patients less than forty years of age.&#13;
Material and Methods:__ampersandsignnbsp;In this study two hundred and nineteen patients with different dystonia were included. Data on demographic profile, clinical and etiological profile was recorded and statistical analysis was done by using descriptive analysis (frequency distribution).&#13;
Results:__ampersandsignnbsp;Out of two hundred and nineteen patients, one hundred thirteen (51.7%)__ampersandsignnbsp;were __ampersandsignlt;26 years of age of onset and one hundred six (48.4%)__ampersandsignnbsp;had __ampersandsigngt;26 years of age of onset with mean age of onset 22.3 years, one hundred seventy six were males and forty four females. Mean duration of illness was 4.4 years. Frequency of different dystonia was focal dystonia 57.72%, multifocal 1.36%, segmental 10%, generalized 29.09%, hemidystonia 3.63%__ampersandsignnbsp;and paroxysmal kinesigenic dystonia 2.72%. Among focal dystoniaWriter__ampersandsignrsquo;s cramp was most common (63%)__ampersandsignnbsp;followed by cervical dystonia (17.32%), and blepharospasm (7%). Among generalized dystonia Wilson__ampersandsignrsquo;s disease was most common etiological factor in 31.25% cases. Primary generalized dystonia was seen in 17.2%__ampersandsignnbsp;cases. MRI was abnormal in all eight cases of hemidystonia. SPECT brain was abnormal in 1 out of four cases of paroxysmal kinesigenic dystonia. DYT1 was positive in four out of eleven patients of primary generalized dystonia.&#13;
Conclusion:__ampersandsignnbsp;Present study showed that focal dystonia were more common even in younger age group with Writers cramp most common among all dystonia followed by cervical dystonia. In hemidystonia structural lesion should always be ruled out.&#13;
</p></abstract><kwd-group><kwd>Dystonia</kwd><kwd> Paroxysmal kinesigenic dystonia</kwd><kwd> Writer’s cramp</kwd></kwd-group></article-meta></front></article>
