<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2d1 20170631//EN" "JATS-journalpublishing1.dtd">
<article xlink="http://www.w3.org/1999/xlink" dtd-version="1.0" article-type="healthcare" lang="en"><front><journal-meta><journal-id journal-id-type="publisher">IJCRR</journal-id><journal-id journal-id-type="nlm-ta">I Journ Cur Res Re</journal-id><journal-title-group><journal-title>International Journal of Current Research and Review</journal-title><abbrev-journal-title abbrev-type="pubmed">I Journ Cur Res Re</abbrev-journal-title></journal-title-group><issn pub-type="ppub">2231-2196</issn><issn pub-type="opub">0975-5241</issn><publisher><publisher-name>Radiance Research Academy</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">2484</article-id><article-id pub-id-type="doi"/><article-id pub-id-type="doi-url">10.31782/IJCRR.2018.10907</article-id><article-categories><subj-group subj-group-type="heading"><subject>Healthcare</subject></subj-group></article-categories><title-group><article-title>Pregnancy Induced Hypertension: A Study on Its Multisystem Involvement&#13;
</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Bhutani</surname><given-names>Karanpreet</given-names></name></contrib><contrib contrib-type="author"><name><surname>Vij</surname><given-names>Chittranjan</given-names></name></contrib><contrib contrib-type="author"><name><surname>Kaur</surname><given-names>Manjeet</given-names></name></contrib><contrib contrib-type="author"><name><surname>Bedi</surname><given-names>Gurdeep Kaur</given-names></name></contrib></contrib-group><pub-date pub-type="ppub"><day>5</day><month>05</month><year>2018</year></pub-date><volume>)</volume><issue/><fpage>27</fpage><lpage>32</lpage><permissions><copyright-statement>This article is copyright of Popeye Publishing, 2009</copyright-statement><copyright-year>2009</copyright-year><license license-type="open-access" href="http://creativecommons.org/licenses/by/4.0/"><license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.</license-p></license></permissions><abstract><p>Objectives:__ampersandsignnbsp;To evaluate and compare Renal, Hepatic and Coagulation profiles in normotensive pregnant females at 20 weeks or more gestation and in cases of Pregnancy induced Hypertension at same gestation.&#13;
Methods:__ampersandsignnbsp;The study was conducted on 100 pregnant females divided into two groups of 50 each:__ampersandsignnbsp;cases of PIH (Study group) and normotensive pregnant females (Control group)__ampersandsignnbsp;and all these females were at 20 weeks or more gestation. Blood sample was collected at the period of gestation when they attended Gynaecology OPD at Rajindra Hospital, Patiala. Blood Urea, S. Creatinine, S. Uric Acid, S. Transaminases and Platelet count were evaluated and compared.&#13;
Results:__ampersandsignnbsp;The mean Blood Urea was 25.92__ampersandsignplusmn;6.16 mg%__ampersandsignnbsp;(study group)__ampersandsignnbsp;compared to 24.60__ampersandsignplusmn;3.21 mg%__ampersandsignnbsp;(control group)__ampersandsignnbsp;(p=0.1823). The difference did not attain statistical significance. The mean S. creatinine was 1.05__ampersandsignplusmn;0.19 mg%__ampersandsignnbsp;(study group)__ampersandsignnbsp;compared to 0.71__ampersandsignplusmn;0.20 mg%__ampersandsignnbsp;(control group)__ampersandsignnbsp;(p__ampersandsignlt;0.0001)__ampersandsignnbsp;while the mean S. uric acid was 5.43__ampersandsignplusmn;1.25 mg%__ampersandsignnbsp;(study group)__ampersandsignnbsp;compared to 3.86__ampersandsignplusmn;0.72 mg%__ampersandsignnbsp;(control group)__ampersandsignnbsp;(p__ampersandsignlt;0.0001)__ampersandsignnbsp;and the difference was statistically highly significant. The mean AST levels were 57.42__ampersandsignplusmn;58.26 IU/L (study group)__ampersandsignnbsp;compared to 25.02__ampersandsignplusmn;6.32 IU/L (control group) (p=0.0002) while the mean ALT levels were 51.80__ampersandsignplusmn;53.98 IU/L(study group)__ampersandsignnbsp;compared to 24.04__ampersandsignplusmn;8.56 IU/L (control group)__ampersandsignnbsp;(p=0.0005). The mean platelet count was 223700.00 __ampersandsignplusmn; 70239.02 mm3 (study group)__ampersandsignnbsp;compared to 314860.00__ampersandsignplusmn;33815.83 mm3 (control group)__ampersandsignnbsp;(p__ampersandsignlt;0.0001). The difference was statistically highly significant.&#13;
Conclusion:__ampersandsignnbsp;Patients with PIH have altered renal, hepatic and coagulation profiles thereby deranging the function of different organs. Timely assessment of various blood parameters in such patients will help in preventing occurrence of PIH and in planning proper intervention to improve both maternal and fetal outcome in established pre-eclamptic women.&#13;
</p></abstract><kwd-group><kwd>Pregnancy induced hypertension</kwd><kwd> Renal</kwd><kwd> Hepatic</kwd><kwd> Coagulation Profiles</kwd></kwd-group></article-meta></front></article>
