Information, education and communication approaches were used in this study to reach the target groups. Nutrition education was provided in the form of text messages integrated with mobile communication, an alternative choice of media already popular among college going girls instead of usual nutrition education practices. 284 college going girls were divided into cases and controls, with proportion of 1:1 ratio, from various institutions with English medium of instruction and using mobile phones were selected from Coimbatore city. A structured and reviewed questionnaire was used to collect background information and to assess the nutritional knowledge status of the target population. A total number of 28 messages were framed. The mHealth (mobile-health) messages were sent using broad band internet connection to the mobile numbers of 142 respondents using Microsoft Excel enabled plug-in for sending bulk SMS for a period of 14 days. The effect of mHealth on the nutritional knowledge of respondents was evaluated by administering a questionnaire. After imparting nutrition education by sending mHealth messages to their mobile phones, there was an increase in the general, therapeutic and adolescent and adult nutrition knowledge of the experimental group when compared to the control group and statistically significant at 1% level. Mobile phones provided a new communication channel for health promotion and community mobilization. mHealth as a nutrition communication tool effectively increased nutritional knowledge among college going girls. mHealth and development of user friendly mobile apps for nutrition communication is very useful in imparting nutrition messages.