Aim: To present the experience of performing Total thyroidectomy for Large Multinodular goitres. Case Report: Series of nine patients with large multinodular goitres treated in our institute between April 2016 and March 2017 were reported here. All of them underwent Total thyroidectomy. The clinical evaluation, intra operative management and complications were analysed retrospectively. Discussion: In this series of nine patients,seven were Females and two were Males, age ranged from 26 to 68 years, seven of those patients had thyroid volume of more than 150 mL by neck ultrasonography and the other two had large goitres with retrosternal extension. Tracheal deviation was found in all nine patients and two patients had tracheal narrowing as well. Thyroid function test revealed three of the patients were hyperthyroid, one hypothyroid, and the rest euthyroid. Technetium(Tc99) scintigraphy showed cold nodule in only one patient out of the three hyperthyroid cases. Fine needle aspiration (FNAC) showed benign pathology (Bethesda II) in six patients, one patient had follicular neoplasm (Bethesda IV). FNAC was not performed in two toxic goitres that did not have cold nodule. Total thyroidectomy was performed successfully in all nine patients. Conclusion: Total Thyroidectomy can be safely performed even in large goitres; no incidence of tracheomalacia was observed; none had permanent hypoparathyroidism or recurrent laryngeal nerve injury.