IJCRRI Journ Cur Res ReInternational Journal of Current Research and ReviewI Journ Cur Res Re2231-21960975-5241Radiance Research Academy2371HealthcareANTIBACTERIAL SCREENING AND PHYTOCHEMICAL ANALYSIS OF CLEOME CILIATA (CAPPARIDACEAE) LEAVES SC.Umerie.Okorie NHSC.EzeaA.NOkpalaononuju)611This article is copyright of Popeye Publishing, 20092009This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.

Ethanolic extract of leaves of Cleome ciliata were studied for phytochemical constituents and in vitro antibacterial activities by agar diffusion method. The phytochemical analysis of the extract revealed the presence of saponins, alkaloids, flavonoids, tannins, steroids, terpenoids, and glycosides. The extract inhibited the growth of Staphylococcus aureus Salmonella paratyphi and Pseudomonas aeruginosa. The flavonoid fraction of the crude sample was active against Staphylococcus aureus, Escherichia coli and Klebsiella pneumoniae, while the tannin fraction was active against Staphylococcus aureus only. The minimum inhibition concentration (MIC) of the ethanolic extract as well as the flavonoid and tannin fractions ranged from 18.14 to 94.02 mg /ml. The results suggest that C. ciliata can be used in the treatment of ailments caused by the test and related organisms.

Cleome ciliata Schmach and Thonn antibacterial screening phytochemical analysis.