Background: Type II diabetes mellitus patients have been shown to affect the multimodal sensory, reflex and motor systems in distal extremities. Studies have examined the mechanosensitivity and vibration threshold in type II diabetes mellitus patients in the lower limb and compared it with normal individuals. There is scanty literature available in comparison of the vibration threshold in the upper limb in type II diabetes mellitus patients with non diabetic individuals. Methods: Thirty type II diabetic individuals were included in the diabetic group and thirty asymptomatic age matched individuals were taken to match the group. Vibration threshold (VT) was measured by tester 1 at the baseline for both the groups using a bioesthesiometer capable of deriving a vibration of 100 Hz. After the VT was taken at three levels 1) at the baseline, the tester performed the upper limb neurodynamic test 1(ULNT1) for each individual. During the sequence of the ULNT1, 2) vibration threshold was measured at initial onset of pain i.e. P1 and 3) short of maximal pain i.e. P2. Results: Repeated measures ANOVA was used to compare the VT differences within group and between groups. There was a statistical significant difference between the vibration threshold of diabetic and non diabetic group at the three levels with a p value __ampersandsignlt; 0.001. Conclusion: Vibration threshold of the upper limb is higher in individuals with type II diabetes mellitus as compared to non diabetic individuals.