IJCRRI Journ Cur Res ReInternational Journal of Current Research and ReviewI Journ Cur Res Re2231-21960975-5241Radiance Research Academy2270HealthcareSYNTHESIS AND BIOLOGICAL SCREENING OF NOVEL ARYLOXYACETIC ACID ANALOGS KaurRamninderKaurKomalpreet311This article is copyright of Popeye Publishing, 20092009This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.

A series of 5-Bromo- 2-formyl phenoxyacetyl amino acids and peptides have been synthesized by coupling of the 5-Bromo- 2-formyl phenoxyacetic acid with amino acid/methyl esters/dipeptides/ tripeptides using DCCas coupling agent and NMM as base. The structures were elucidated FTIR and 1HNMR .The newly synthesized compounds were evaluated for their antibacterial, antifungal and anthelminitic activities. The compounds (2, 6, 11 and 13) were found to exihibit potent antibacterial activity against Bacillus subtilis, Staphylococcus aureus (gram positive bacteria) and Escherichia coli (gram negative) bacterias.Thecompounds (5, 6 and 13) were found to exihibit potent antifungal activity against Candida albicans and Aspergillus niger. The moderate to good anthelminitic activity was shown by the synthesized compounds (7 and 13) against Eudrilus spieces.

Phenoxyacetic acid amino acids antibacterial antifungal and anthelminitic.