Ethanolic extracts of Hedychium spichatum rhizomes and Cucurbita maxima seeds were taken for In vitro comparative studies on Anthelmintic activity against Pheritima posthuma. Different concentrations (25, 50, 100 mg/ml) of both the extracts were used for the activity. Different Albendazole concentrations (25, 50, 100 mg/ml) were used as a reference standard and normal saline (0.9% NaCl) was used for control treatment. The result was expressed in terms of time in minutes to report paralysis time and death time of earthworms. The data obtained from the study indicates towards the anthelmintic activity, supporting folk use of both the plants when compared to standard. The results also established, a more potent candidature of Cucurbita maxima as compare to Hedychium spichatum.