Most of the chemical entities that are being discovered are lipophilic in nature and have poor aqueous solubility, there by posing problems in their formulation into delivery systems. Because of their low aqueous solubility and high permeability, dissolution and/or release rate from the delivery system forms the rate-limiting step in their absorption and systemic availability. This frequently results in potentially important products not reaching the market or not achieving their full potential. Transdermal drug delivery provides the promising delivery system for those drugs. It provides better patient compliance by avoiding invasiveness, prolonging plasma drug level, bypass first pass effect, reduced side effects and easy termination of therapy. Interest in organogels has increased in a wide variety of fields including chemistry, biotechnology and pharmaceutics. It is more reasonable to look for a carrier that interacts with the skin such that it allows various molecules to pass into the skin. In this paper, which follows a review on investigation of lecithin organogels as carriers for the transdermal transport of drugs having problems mentioned above. The general properties of lecithin organogels, method of preparation and its characterization have been discussed. The potential use of lecithin organogels for the transdermal transport of many therapeutic agents have also been discussed in the present review.