The need of reliable communication, where no data loss, no duplication and no out of order delivery occurs becomes a vital necessity of most application programs in all networks. Transmission control protocol provides error free reliable communication for wired networks. The decision of deployin transmission control protocol in ad hoc network becomes difficult due to the availability of its different variants with Mobile Ad hoc Network routing protocols especially when mobility is an issue. This paper analyzes the advanced and sophisticated transmission control protocol Variants with Ad hoc On-demand Distance Vector routing protocol to measure different parameters required for reliable communication such as the finest performance of packets delivery rate, average end-toend delay, and packet dropping. Finally from various differentiable results, an enhanced combination of transmission control protocol variant Vegas and Ad hoc On-demand Distance Vector routing protocol will be chosen and refined to achieve desirable output. The refinement proves to be the better solution of deployable protocols of Transmission Control Protocol in Mobile Ad hoc Network with decidedly mobile environment.