There are remarkable forward strides in the manufacturing process with the tremendous technological innovations. In order to increase productivity, enhance quality and reduce cost, machine tool have to work free of any malfunction. Vibration responses are the proven measure of the malfunction. The main objective of this study is dedicated to the experimental vibration analysis of the spindle bearing assembly with self exited vibration. Experimental Modal analysis was carried out to obtain the natural frequency and vibration responses are investigated at various parametric levels and combinationsusing LabVIEW software. The parameters in the investigation include feed, depth of cut, and cutting speed.Output parametris is surface finish and vibration level. Experimental data collected are tested with anlayis of variance(ANOVA) Taguchi design of experiments was used to optimize the process parameter for the responses, surface roughness and vibration level. Regression model developed serves in prediction for the responsesOn the completion of the experimental test ANOVA is used to validate the results.