New investigations in the field of protein structures, bacterial exudes and prion research; and related experimental indications derived suggest that when infectious forms of prion plaques placed in or with resistance __ampersandsignndash; providing variant form(s) are irradiated with appropriate laser power; reversions of prion plaques into structures like coils, helices, etc. may hypothetically take place. These structures are less stable than the beta sheets, hence more susceptible to being biologically cleared off the plaque residues. This provides for a means to effectively cure or prevent prion __ampersandsignndash; like amyloid plaque related diseases; with further implications for physical biology.