In this work, an experimental work was investigated on the R-404A which is eco friendly refrigerant and has zero ozone depletion potential and low global warming potential than R-134a used in a domestic refrigerator without any system reconstruction. The refrigerator performance was then investigated using energy consumption test and freeze capacity test. The results indicate that R-404A work normally and safely in the refrigerator. The refrigerator performance was better than the pure R134a, thus R-404A refrigerant in domestic refrigerators is feasible and can replace the R-134a.