IJCRRI Journ Cur Res ReInternational Journal of Current Research and ReviewI Journ Cur Res Re2231-21960975-5241Radiance Research Academy2039HealthcareSYNTHESIS AND THIN LAYER CHROMATOGRAPHY OF SOME NEW D-HOMO AZA STEROIDAL COMPOUNDS SinghPawanpreetKaurSatvinderKapoorV.KBhardwajT.R28122011)212219This article is copyright of Popeye Publishing, 20092009This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.

The various D-homo aza steroidal compounds PS-3 to PS-9 with nitrogen atoms attached to positions 3 and 17a were synthesized by us in our laboratory using (25R)-5-spirosten-3__ampersandsignbeta;- ol (Diosgenin) as a starting material. The compounds PS-6 and PS-9 are having this nitrogen atom quaternized. These compounds are evaluated for their TLC1 data using various solvent systems. The detailed synthesis, spectroscopic and TLC data for the synthesized compounds were reported here.

Steroidal lactams; quaternized nitrogen; TLC; D-homo; solvent system.