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<article xlink="http://www.w3.org/1999/xlink" dtd-version="1.0" article-type="healthcare" lang="en"><front><journal-meta><journal-id journal-id-type="publisher">IJCRR</journal-id><journal-id journal-id-type="nlm-ta">I Journ Cur Res Re</journal-id><journal-title-group><journal-title>International Journal of Current Research and Review</journal-title><abbrev-journal-title abbrev-type="pubmed">I Journ Cur Res Re</abbrev-journal-title></journal-title-group><issn pub-type="ppub">2231-2196</issn><issn pub-type="opub">0975-5241</issn><publisher><publisher-name>Radiance Research Academy</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">2038</article-id><article-id pub-id-type="doi"/><article-id pub-id-type="doi-url"/><article-categories><subj-group subj-group-type="heading"><subject>Healthcare</subject></subj-group></article-categories><title-group><article-title>A STUDY OF CLINICAL PATTERNS __ampersandsign PATCH TEST IN ADVERSE CUTANEOUS DRUG REACTION&#13;
</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>gupta</surname><given-names>Kalpana</given-names></name></contrib><contrib contrib-type="author"><name><surname>Khare</surname><given-names>A K</given-names></name></contrib><contrib contrib-type="author"><name><surname>Gupta</surname><given-names>Lalit</given-names></name></contrib><contrib contrib-type="author"><name><surname>Mittal</surname><given-names>Asit</given-names></name></contrib><contrib contrib-type="author"><name><surname>Shrimali</surname><given-names>Lalit</given-names></name></contrib><contrib contrib-type="author"><name><surname>Gupta</surname><given-names>Pankaj</given-names></name></contrib></contrib-group><pub-date pub-type="ppub"><day>28</day><month>12</month><year>2011</year></pub-date><volume>)</volume><issue/><fpage>207</fpage><lpage>211</lpage><permissions><copyright-statement>This article is copyright of Popeye Publishing, 2009</copyright-statement><copyright-year>2009</copyright-year><license license-type="open-access" href="http://creativecommons.org/licenses/by/4.0/"><license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.</license-p></license></permissions><abstract><p>Objective: In the present scenario the number of controlled and systematic studies on the role&#13;
of patch test in adverse cutaneous drug reaction (ACDR) is limited. Objective in this study, we&#13;
planned to evaluate the patch test for the identification of causative drug in drug reaction with&#13;
possibly delayed type of hypersensitivity (DTH). Methods: The cases of ACDR those having&#13;
DTH such as maculopapular rash (MPR), fixed drug eruption (FDE), erythema multiforme,&#13;
lichenoid dermatitis (LD), Steven – Johnson syndrome (SJS), Toxic epidermal necrolysis&#13;
(TEN) and exfoliative dermatitis (Exf. DER) were taken in study. Thirty two patients (21 Males&#13;
__ampersandsign 11 Females) were patch tested with market preparation of 28 drugs having 1% and 5%&#13;
concentration. Result and conclusion: The incidence of ACDR amongst dermatology&#13;
outpatients was approximately 1%. The percentage of DTH reaction amongst ACDR patients&#13;
was 52.38%. The FDE was the commonest pattern seen in DTH patients. Five out of thirty two&#13;
patients (15.62%) tested positive to the suspected drugs. Three out of 26 patients with FDE&#13;
showed positive patch test at clinically normal site while both, the patients with MPR tested&#13;
positive. None of the patients with SJS, Exf. DER __ampersandsign LDR showed positive patch test. More&#13;
prospective study regarding patch test in ACDR is needed.&#13;
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