Objective __ampersandsignmdash; To study the clinical profile of patients with metabolic syndrome and find out the association of CRP level with components of the metabolic syndrome. Research Design And Methods__ampersandsignmdash; We conducted a cross-sectional prospective study in 50 cases of metabolic syndrome randomly selected from medical wards of a tertiary care hospital. Total cholesterol (TC), HDL cholesterol, triglycerides, BMI, waist circumference and prevalence of diabetes and hypertension were assessed. To define the metabolic syndrome we used modified ATP III criteria recommended in AHA/NHLBI statement. Complete information for the five variables needed to assess the metabolic syndrome was collected. CRP was measured by latex enhanced immunoturbidimetric assay (high sensitivity CRP assay). Results__ampersandsignmdash; Higher waist circumference cases had higher mean hs-CRP (3.235 Vs 1.950, P __ampersandsignlt;0.0001). Elevated diastolic blood pressure cases had higher mean hs-CRP level (3.264 Vs 2.221, P __ampersandsignlt; 0.05) Conclusions__ampersandsignmdash;Waist circumference was significantly and independently associated with high hs-CRP levels. The data suggest that hs-CRP value significantly increased with increase in the number of features of metabolic syndrome.