Objective: Mental nerve is sensory nerve of lower lip, gingiva and vestibule. Mental nerve emerges through the mental foramen, a foramen on the antero lateral aspect of body of mandible. To anesthetise the mental nerve local anesthetic must be injected at the point where it emerges out fr om mental foramen. Hence it was decided to study the mental foramen. Methods: Sixty human dry mandibles were studied to measure the distance of mental foramen from symphysis menti, alveolar ridge, base of mandible and posterior border of ramus of mandible. The shape, direction of mental foramen were recorded. Location of mental foramen in relation to the lower teeth was also recorded and all the parameters were tabulated and analysed. Results and Conclusion: According to the present study mental foramen was located 1.3cm below the alveolar ridge, 1.25 cm above the base of mandible, 2.5 cm postero-lateral to symphysis menti, 6.4 cm anterior to the posterior border of ramus and was most commonly in line with 2nd lower premolar tooth. The shape was round and direction was postero-superior in most of the cases.