Purpose: To compare changes in physical performances (strength, flexibility and balance) between healthy Pre-Menopausal (40-45 years) and Post-Menopausal females (45-55 years) with natural history of menopause. Methods: Sixty pre and postmenopausal females were included. Strength was measured by hand held dynamometer, Flexibility with flexometer and Balance through postural sway. Results: Analysis of Variance (ANOVA), student paired t-test and Bonferroni test were used for the analysis. Level of significance __ampersandsignlt; 0.05 was considered statistically significant with 95% CI. No significant difference was found for strength (p=0.081) and flexibility (p=0.116). But, loss of Balance (p=0.000) was found to be highly significant among the Post Menopausals. Conclusion: Lower limb muscles flexibility and upper limb strength did not show any significant changes among immediate Post Menopausal females; but__ampersandsignnbsp;static balance was significantly affected among the Post Menopausals causing diminished Physical Performance with age advancement.