The Revised National Tuberculosis Control Programme introduced in 1993 lays more emphasis on good quality diagnosis by direct sputum smear microscopy and quality drugs, through standardized short course chemotherapy regimens administered under direct observation along with systematic monitoring and evaluation. The goal of the Revised National Tuberculosis Control Programme is to cure at least 85% of new sputum smear positive patients detected and to detect at least 70% of all such patients after the goal for cure rate has been met. No studies have been done on evaluation of Revised National Tuberculosis Control Programme and reasons for default in these areas. Objective of this study to know the reasons for default of the patients put under Revised National Tuberculosis Control Programme. Materials and method: This study carried over for one year one month (November 1st 2004 to 31st December 2005). The data collected by using pre-designed and pretested proforma. The first visit was done when the patient was registered in the Primary Health Centre and started on the treatment. Second visit i.e. First follow-up visit was done at the end of Intensive Phase and the data was collected regarding the scheduled intake of drugs, result of 1st follow-up sputum examination and about defaulters if any. Second follow-up visit was done in the middle of continuation phase and the data was collected regarding the scheduled intake of drugs, result of 2nd follow-up sputum examination and defaulters if any. Fourth visit i.e. third follow-up visit was done at the end of Continuation Phase and the data was collected regarding the scheduled intake of drugs, result of sputum examination at the end of the treatment, about defaulters if any and outcome of the treatment. Results: Out of 69 defaulter cases majority 63% of them were males, the main reason for treatment failure were illiteracy (42%), marital status (79%), Class V family (58%), complaining of acidity and vomiting (63%). habit of smoking (31%) and smokeless tobacco(15%). These are the significant reasons for treatment failure.