Objectives: It is known that changes in the body positions leads to the various changes in the cardio vascular system. It is also known that many factors influence on individuals BP measurement, however BP is constantly changes from one position to another. Change in positions well known to cause change in intravascular and intra cardiac volumes and pressures, and in neurohumoral activity. Surprisingly there is little information available on the BP changes in various positions between hypertensive and normotensive individuals. Purpose of the study to compare mean arterial blood pressure response between supine, sitting, standing and supine with crossed leg positions. Methods: 100 volunteers,50 hypertensive and 50 normotensive, male __ampersandsignndash; 49, Female __ampersandsignndash; 51, age range 18 __ampersandsignndash; 35 years, with mean age of normotensive individuals 22.74__ampersandsignplusmn; 2.90 and mean age of hypertensive individuals were 27.70 __ampersandsignplusmn; 3.19 . Four different positions were used in this study: Sitting, Standing, Supine and supine with cross leg. Blood pressure measured by standardized mercury sphygmomanometer and MABP value was calculated as per formula. Results: Comparison of changes in MABP scores in different positions between hypertensive and__ampersandsignnbsp;normotensive individuals shows p __ampersandsignndash; value __ampersandsignlt; 0.01 which were statistically significant. Conclusion: The study shows that there is significant difference of positions on MABP response between hypertensive and normotensive individuals. The study concluded that in standing position MABP is lower than other positions and supine position has higher MABP values.